Factors Associated with Acute Kidney Injury in Cirrhotics Patients at the Departmental University Hospital of Borgou and Alibori (Benin)
Introduction: Acute kidney injury is one of the major complications that can occur during liver cirrhosis.
Objective: to study the frequency and factors associated with acute kidney injury in CHUD-B/A cirrhotic patients in 2022.
Patients and methods: This was a cross-sectional, descriptive study with prospective data collection over a period from February 1 to June 30, 2022. A systematic recruitment of cirrhotic patients received in consultation and in hospitalization was made. AKI was defined according to the ADQI- IAC classification. Statistical analysis was performed using SPSS 21 software. The association between the identified factors and the variable of interest was determined by the Odds Ratio (OR) and its 95% confidence interval.
Results: A total of 73 cirrhotic patients were included and 14 of them had AKI. The frequency of AKI in cirrhotics was 19.2%. The mean age was 48.6 ± 16.9 years with a sex ratio of 13. Factors associated with AKI were hepatic encephalopathy (p=0.006) and Child-Pugh C score (p=0.031).
Conclusion: Acute kidney injury among cirrhotic patients is highly frequent. Its screening should be systematic for cirrhosis patients in order to improve their medical care and survival.
DOI: 10.29245/2767-5149/2025/1.1124 View / Download Pdf